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Expression and purification of functional insulin and insulin-like growth factor 1 holoreceptors from mammalian cells

The insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF1R) are receptor tyrosine kinases (RTKs) involved in the regulation of many important cellular processes. The current proposed models of activation are derived from structural studies using soluble extracellular domains and cyto...

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Detalhes bibliográficos
Publicado no:Anal Biochem
Main Authors: Delle Bovi, Richard J., Miller, W. Todd
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701837/
https://ncbi.nlm.nih.gov/pubmed/28830678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ab.2017.08.011
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