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In-vivo evaluation in rats of colon-specific microspheres containing 5-fluorouracil
The aims of this investigation were to determine the distribution in the gastrointestinal (GI) tract of Eudragit S-100 encapsulated colon-specific sodium alginate microspheres containing 5-fluorouracil (5-FU) in rats, and to perform pharmacokinetic and pharmacodynamic studies. Comparisons were with...
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| Publicado no: | J Pharm Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701816/ https://ncbi.nlm.nih.gov/pubmed/18416938 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1211/jpp.60.5.0007 |
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