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Structure Activity Relationship of Heparin Mimicking Polymer p(SS-co-PEGMA): Effect of Sulfonation and Polymer Size on FGF2-Receptor Binding()

Fibroblast growth factor-2 (FGF2) is a heparin binding protein that plays a role in a range of biological functions such as wound healing and bone regeneration. Heparin, a highly sulfated glycosaminoglycan, is required for FGF2 to bind to its receptor. Therefore, polymeric mimics of heparin are wide...

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Detalhes bibliográficos
Publicado no:Polym Chem
Main Authors: Paluck, Samantha J., Maynard, Heather D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701782/
https://ncbi.nlm.nih.gov/pubmed/29181096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/C7PY00861A
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