Polymorphism of MSH2 Gly322Asp and MLH1 –93G>A in non-familial colon cancer – a case-controlled study

INTRODUCTION: Our aim was to determine the effect of the single nucleotide polymorphisms (SNP) –93G>A of the MLH1 gene (rs1800734) and Gly322Asp of the MSH2 gene (rs4987188) on the risk of colon cancer (CC) and identify any relationship with clinical factors. MATERIAL AND METHODS: The study inclu...

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Bibliographic Details
Published in:Arch Med Sci
Main Authors: Mik, Michal, Dziki, Lukasz, Malinowska, Katarzyna, Trzcinski, Radzislaw, Majsterek, Ireneusz, Dziki, Adam
Format: Artigo
Language:Inglês
Published: Termedia Publishing House 2017
Subjects:
Basic Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701696/
https://ncbi.nlm.nih.gov/pubmed/29181059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/aoms.2017.67024
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