HashClone: a new tool to quantify the minimal residual disease in B-cell lymphoma from deep sequencing data

BACKGROUND: Mantle Cell Lymphoma (MCL) is a B cell aggressive neoplasia accounting for about the 6% of all lymphomas. The most common molecular marker of clonality in MCL, as in other B lymphoproliferative disorders, is the ImmunoGlobulin Heavy chain (IGH) rearrangement, occurring in B-lymphocytes....

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: Beccuti, Marco, Genuardi, Elisa, Romano, Greta, Monitillo, Luigia, Barbero, Daniela, Boccadoro, Mario, Ladetto, Marco, Calogero, Raffaele, Ferrero, Simone, Cordero, Francesca
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701356/
https://ncbi.nlm.nih.gov/pubmed/29169317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-017-1923-2
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