Notoginsenoside R1 Alleviates Oxygen–Glucose Deprivation/Reoxygenation Injury by Suppressing Endoplasmic Reticulum Calcium Release via PLC

As documented in our previous study, notoginsenoside R1 (NGR1) can inhibit neuron apoptosis and the expression of endoplasmic reticulum (ER) stress-associated pro-apoptotic proteins in hypoxic–ischemic encephalopathy. Recent evidence indicates that the Phospholipase C (PLC)/inositol 1,4,5-trisphosph...

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Pubblicato in:Sci Rep
Autori principali: Wang, Yan, Tu, Liu, Li, Yingbo, Chen, Di, Liu, Zhao, Hu, Xuelian, Wang, Shali
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701215/
https://ncbi.nlm.nih.gov/pubmed/29176553
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16373-7
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