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Isochlorogenic acid C prevents enterovirus 71 infection via modulating redox homeostasis of glutathione

Enterovirus 71 (EV71) is a key pathogen of hand, foot and mouth disease (HFMD) in children under 6 years of age. The antiviral potency of antioxidant isochlorogenic acid C (ICAC) extracted from foods was evaluated in cellular and animal models. First, the cytotoxicity of ICAC on Vero cells was inves...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Cao, Zeyu, Ding, Yue, Cao, Liang, Ding, Gang, Wang, Zhenzhong, Xiao, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701158/
https://ncbi.nlm.nih.gov/pubmed/29176678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16446-7
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