Microneedle-array patches loaded with dual mineralized protein/peptide particles for type 2 diabetes therapy

The delivery of therapeutic peptides for diabetes therapy is compromised by short half-lives of drugs with the consequent need for multiple daily injections that reduce patient compliance and increase treatment cost. In this study, we demonstrate a smart exendin-4 (Ex4) delivery device based on micr...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Chen, Wei, Tian, Rui, Xu, Can, Yung, Bryant C., Wang, Guohao, Liu, Yijing, Ni, Qianqian, Zhang, Fuwu, Zhou, Zijian, Wang, Jingjing, Niu, Gang, Ma, Ying, Fu, Liwu, Chen, Xiaoyuan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701150/
https://ncbi.nlm.nih.gov/pubmed/29176623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01764-1
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