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Systems analysis of latent HIV reversal reveals altered stress kinase signaling and increased cell death in infected T cells
Viral latency remains the most significant obstacle to HIV eradication. Clinical strategies aim to purge the latent CD4+ T cell reservoir by activating viral expression to induce death, but are undercut by the inability to target latently infected cells. Here we explored the acute signaling response...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5701066/ https://ncbi.nlm.nih.gov/pubmed/29170390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15532-0 |
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