Genome-wide meta-analysis in Japanese populations identifies novel variants at the TMC6–TMC8 and SIX3–SIX2 loci associated with HbA(1c)

Glycated haemoglobin (HbA(1c)) is widely used as a biomarker for the diagnosis of diabetes, for population-level screening, and for monitoring the glycaemic status during medical treatment. Although the heritability of HbA(1c) has been estimated at ~55–75%, a much smaller proportion of phenotypic va...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Hachiya, Tsuyoshi, Komaki, Shohei, Hasegawa, Yutaka, Ohmomo, Hideki, Tanno, Kozo, Hozawa, Atsushi, Tamiya, Gen, Yamamoto, Masayuki, Ogasawara, Kuniaki, Nakamura, Motoyuki, Hitomi, Jiro, Ishigaki, Yasushi, Sasaki, Makoto, Shimizu, Atsushi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5701039/
https://ncbi.nlm.nih.gov/pubmed/29170429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16493-0
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