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Cryo-EM structure of Saccharomyces cerevisiae target of rapamycin complex 2
The target of rapamycin (TOR) kinase assembles into two distinct multiprotein complexes, conserved across eukaryote evolution. In contrast to TOR complex 1 (TORC1), TORC2 kinase activity is not inhibited by the macrolide rapamycin. Here, we present the structure of Saccharomyces cerevisiae TORC2 det...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5700991/ https://ncbi.nlm.nih.gov/pubmed/29170376 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01862-0 |
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