PDGFR Signaling Mediates Hyperproliferation and Fibrotic Responses of Subsynovial Connective Tissue Cells in Idiopathic Carpal Tunnel Syndrome

Fibrosis of the subsynovial connective tissue (SSCT) is a pathognomonic change in carpal tunnel syndrome (CTS). Identification of molecular targets and anti-fibrotic therapies could provide new treatment strategies for CTS. The contribution of SSCT cells to fibrosis and the signaling pathways that i...

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Publicado en:Sci Rep
Autores principales: Saito, Yuki, Chikenji, Takako, Ozasa, Yasuhiro, Fujimiya, Mineko, Yamashita, Toshihiko, Gingery, Anne, Iba, Kousuke
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700922/
https://ncbi.nlm.nih.gov/pubmed/29170419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16443-w
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