Acylated ghrelin treatment normalizes skeletal muscle mitochondrial oxidative capacity and AKT phosphorylation in rat chronic heart failure

BACKGROUND: Chronic heart failure (CHF) is associated with skeletal muscle abnormalities contributing to exercise intolerance, muscle loss, and negative impact on patient prognosis. A primary role has been proposed for mitochondrial dysfunction, which may be induced by systemic and tissue inflammati...

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Publicat a:J Cachexia Sarcopenia Muscle
Autors principals: Barazzoni, Rocco, Gortan Cappellari, Gianluca, Palus, Sandra, Vinci, Pierandrea, Ruozi, Giulia, Zanetti, Michela, Semolic, Annamaria, Ebner, Nicole, von Haehling, Stephan, Sinagra, Gianfranco, Giacca, Mauro, Springer, Jochen
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700435/
https://ncbi.nlm.nih.gov/pubmed/29098797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcsm.12254
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