Genetics of Nevirapine Metabolic Pathways at Steady State in HIV-Infected Cambodians

Nevirapine is metabolized by several hepatic cytochrome P450 (CYP) isoforms to generate four primary hydroxylated metabolites: 2-hydroxynevirapine, 3-hydroxynevirapine, 8-hydroxynevirapine, and 12-hydroxynevirapine. The present study characterized associations between genetic polymorphisms and metab...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Antimicrob Agents Chemother
Prif Awduron: Eloy, Philippine, Tessier, Adrien, Fan-Havard, Patty, Chou, Monidarin, Verstuyft, Céline, Taburet, Anne-Marie, Haas, David W., Bertrand, Julie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2017
Pynciau:
Antiviral Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700353/
https://ncbi.nlm.nih.gov/pubmed/28947469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00733-17
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