Sustained Ex Vivo Susceptibility of Plasmodium falciparum to Artemisinin Derivatives but Increasing Tolerance to Artemisinin Combination Therapy Partner Quinolines in The Gambia

Antimalarial interventions have yielded a significant decline in malaria prevalence in The Gambia, where artemether-lumefantrine (AL) has been used as a first-line antimalarial for a decade. Clinical Plasmodium falciparum isolates collected from 2012 to 2015 were analyzed ex vivo for antimalarial su...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Amambua-Ngwa, Alfred, Okebe, Joseph, Mbye, Haddijatou, Ceesay, Sukai, El-Fatouri, Fatima, Joof, Fatou, Nyang, Haddy, Janha, Ramatoulie, Affara, Muna, Ahmad, Abdullahi, Kolly, Olimatou, Nwakanma, Davis, D'Alessandro, Umberto
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2017
Fag:
Epidemiology and Surveillance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700332/
https://ncbi.nlm.nih.gov/pubmed/28971859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00759-17
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