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PKCδ silencing alleviates saturated fatty acid induced ER stress by enhancing SERCA activity

Protein kinase C δ (PKCδ) plays an important role in nonalcoholic fatty liver disease (NAFLD), however, the mechanism remains unknown. The present study explored the role of PKCδ in NAFLD development and investigated the relationships between PKCδ, calcium homeostasis, and endoplasmic reticulum (ER)...

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Detalhes bibliográficos
Publicado no:Biosci Rep
Main Authors: Lai, Shujie, Li, Yan, Kuang, Yi, Cui, Hongli, Yang, Yang, Sun, Wenjing, Liu, Kaijun, Chen, Dongfeng, Yan, Qixian, Wen, Liangzhi
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5700272/
https://ncbi.nlm.nih.gov/pubmed/29046367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20170869
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