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Telomerase activity is required for the telomere G-overhang structure in Trypanosoma brucei
Trypanosoma brucei causes fatal human African trypanosomiasis and evades the host immune response by regularly switching its major surface antigen, VSG, which is expressed exclusively from subtelomeric loci. Telomere length and telomere proteins play important roles in regulating VSG silencing and s...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5700094/ https://ncbi.nlm.nih.gov/pubmed/29167542 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16182-y |
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