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Hypoxia Driven Glycation: Mechanisms and Therapeutic Opportunities
Tumor masses are deprived of oxygen and characterized by enhanced glucose uptake followed by glycolysis. Elevated glucose levels induce non-enzymatic glycosylation or glycation of proteins which leads to accumulation of advanced glycation end products (AGE). These AGE molecules bind to their respect...
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| Publicat a: | Semin Cancer Biol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699980/ https://ncbi.nlm.nih.gov/pubmed/28546110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2017.05.008 |
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