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The Interplay of Host Genetics and the Gut Microbiota Underlying the Onset and Clinical Presentation of Inflammatory Bowel Disease

OBJECTIVE: Patients with Inflammatory Bowel Disease (IBD) display substantial heterogeneity in clinical characteristics. We hypothesize that individual differences in the complex interaction of the host genome and the gut microbiota can explain the onset and the heterogeneous presentation of IBD. Th...

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發表在:Gut
Main Authors: Imhann, Floris, Vila, Arnau Vich, Bonder, Marc Jan, Fu, Jingyuan, Gevers, Dirk, Visschedijk, Marijn C., Spekhorst, Lieke M., Alberts, Rudi, Franke, Lude, van Dullemen, Hendrik M., Ter Steege, Rinze W.F., Huttenhower, Curtis, Dijkstra, Gerard, Xavier, Ramnik J., Festen, Eleonora A.M., Wijmenga, Cisca, Zhernakova, Alexandra, Weersma, Rinse K.
格式: Artigo
語言:Inglês
出版: 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699972/
https://ncbi.nlm.nih.gov/pubmed/27802154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2016-312135
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