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Opposing actions of AKT isoforms in vascular smooth muscle injury and therapeutic response

OBJECTIVE: Drug-eluting stent delivery of mTORC1 inhibitors is highly effective in preventing intimal hyperplasia following coronary revascularization, but adverse effects limit utility for systemic vascular disease. Understanding the mechanism of action may lead to new treatment strategies. We have...

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Bibliografiske detaljer
Udgivet i:Arterioscler Thromb Vasc Biol
Main Authors: Jin, Yu, Xie, Yi, Ostriker, Allison C., Zhang, Xinbo, Liu, Renjing, Lee, Monica Y., Leslie, Kristen L., Tang, Waiho, Du, Jing, Lee, Seung Hee, Wang, Yingdi, Sessa, William C., Hwa, John, Yu, Jun, Martin, Kathleen A.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699966/
https://ncbi.nlm.nih.gov/pubmed/29025710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.117.310053
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