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Induction of fibroblast growth factor 21 does not require activation of the hepatic X-box binding protein 1 in mice
OBJECTIVE: Fibroblast growth factor 21 (FGF21), a key regulator of the metabolic response to fasting, is highly induced by endoplasmic reticulum (ER) stress. The X-box binding protein 1 (Xbp1) is one of several ER stress proteins that has been shown to directly activate the FGF21 promoter. We aimed...
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| Izdano u: | Mol Metab |
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| Glavni autori: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Elsevier
2017
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5699917/ https://ncbi.nlm.nih.gov/pubmed/29157602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.09.006 |
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