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MPSR1 is a cytoplasmic PQC E3 ligase for eliminating emergent misfolded proteins in Arabidopsis thaliana

Ubiquitin E3 ligases are crucial for eliminating misfolded proteins before they form cytotoxic aggregates that threaten cell fitness and survival. However, it remains unclear how emerging misfolded proteins in the cytoplasm can be selectively recognized and eliminated by E3 ligases in plants. We fou...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Main Authors: Kim, Jong Hum, Cho, Seok Keun, Oh, Tae Rin, Ryu, Moon Young, Yang, Seong Wook, Kim, Woo Taek
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5699081/
https://ncbi.nlm.nih.gov/pubmed/29087340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1713574114
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