A Peptidergic Circuit Links the Circadian Clock to Locomotor Activity

The mechanisms by which clock neurons in the Drosophila brain confer an ~24-hr rhythm onto locomotor activity are unclear, but involve the neuropeptide diuretic hormone 44 (DH44), an ortholog of corticotropin-releasing factor. Here we identified DH44 receptor 1 as the relevant receptor for rest:acti...

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Udgivet i:Curr Biol
Main Authors: King, Anna N., Barber, Annika F., Smith, Amelia E., Dreyer, Austin P., Sitaraman, Divya, Nitabach, Michael N., Cavanaugh, Daniel J., Sehgal, Amita
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698909/
https://ncbi.nlm.nih.gov/pubmed/28669757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.05.089
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