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Contribution of In Vivo and Organotypic 3D Models to Understanding the Role of Macrophages and Neutrophils in the Pathogenesis of Psoriasis

Psoriasis, a common chronic immune-mediated skin disease, is histologically characterized by a rapid keratinocyte turnover and differentiation defects. Key insights favor the idea that T cells are not the only key actors involved in the inflammatory process. Innate immune cells, more precisely neutr...

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Bibliographic Details
Published in:Mediators Inflamm
Main Authors: Lorthois, Isabelle, Asselineau, Daniel, Seyler, Nathalie, Pouliot, Roxane
Format: Artigo
Language:Inglês
Published: Hindawi 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698795/
https://ncbi.nlm.nih.gov/pubmed/29249871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/7215072
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