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Biosimilars: Key regulatory considerations and similarity assessment tools

A biosimilar drug is defined in the US Food and Drug Administration (FDA) guidance document as a biopharmaceutical that is highly similar to an already licensed biologic product (referred to as the reference product) notwithstanding minor differences in clinically inactive components and for which t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Biotechnol Bioeng
Hauptverfasser: Kirchhoff, Carol F., Wang, Xiao‐Zhuo Michelle, Conlon, Hugh D., Anderson, Scott, Ryan, Anne M., Bose, Arindam
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698755/
https://ncbi.nlm.nih.gov/pubmed/28842986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26438
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