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Prediction of Reduction Potentials of Copper Proteins with Continuum Electrostatics and Density Functional Theory

Blue copper proteins, such as azurin, show dramatic changes in Cu(2+)/Cu(+) reduction potential upon mutation over the full physiological range. Hence, they have important functions in electron transfer and oxidation chemistry and have applications in industrial biotechnology. The details of what de...

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Veröffentlicht in:Chemistry
Hauptverfasser: Fowler, Nicholas J., Blanford, Christopher F., Warwicker, Jim, de Visser, Sam P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698706/
https://ncbi.nlm.nih.gov/pubmed/28815759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201702901
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