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Discrete False-Discovery Rate Improves Identification of Differentially Abundant Microbes

Differential abundance testing is a critical task in microbiome studies that is complicated by the sparsity of data matrices. Here we adapt for microbiome studies a solution from the field of gene expression analysis to produce a new method, discrete false-discovery rate (DS-FDR), that greatly impro...

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Detalhes bibliográficos
Publicado no:mSystems
Main Authors: Jiang, Lingjing, Amir, Amnon, Morton, James T., Heller, Ruth, Arias-Castro, Ery, Knight, Rob
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698492/
https://ncbi.nlm.nih.gov/pubmed/29181446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mSystems.00092-17
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