β-adrenergic stimulation augments transmural dispersion of repolarization via modulation of delayed rectifier currents I(Ks) and I(Kr) in the human ventricle

Long QT syndrome (LQTS) is an inherited or drug induced condition associated with delayed repolarization and sudden cardiac death. The cardiac potassium channel, I(Kr), and the adrenergic-sensitive cardiac potassium current, I(Ks), are two primary contributors to cardiac repolarization. This study a...

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Publicado no:Sci Rep
Main Authors: Kang, C., Badiceanu, A., Brennan, J. A., Gloschat, C., Qiao, Y., Trayanova, N. A., Efimov, I. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698468/
https://ncbi.nlm.nih.gov/pubmed/29162896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-16218-3
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