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miRDDCR: a miRNA-based method to comprehensively infer drug-disease causal relationships

Revealing the cause-and-effect mechanism behind drug-disease relationships remains a challenging task. Recent studies suggested that drugs can target microRNAs (miRNAs) and alter their expression levels. In the meanwhile, the inappropriate expression of miRNAs will lead to various diseases. Therefor...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Chen, Hailin, Zhang, Zuping, Peng, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698443/
https://ncbi.nlm.nih.gov/pubmed/29162848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15716-8
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