The corepressor NCOR1 regulates the survival of single-positive thymocytes

Nuclear receptor corepressor 1 (NCOR1) is a transcriptional regulator bridging repressive chromatin modifying enzymes with transcription factors. NCOR1 regulates many biological processes, however its role in T cells is not known. Here we show that Cd4-Cre-mediated deletion of NCOR1 (NCOR1 cKO(Cd4))...

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Publicat a:Sci Rep
Autors principals: Müller, Lena, Hainberger, Daniela, Stolz, Valentina, Hamminger, Patricia, Hassan, Hammad, Preglej, Teresa, Boucheron, Nicole, Sakaguchi, Shinya, Wiegers, G. Jan, Villunger, Andreas, Auwerx, Johan, Ellmeier, Wilfried
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698297/
https://ncbi.nlm.nih.gov/pubmed/29162920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-15918-0
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