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Dysregulation of the miR-146a-Smad4 axis impairs osteogenesis of bone mesenchymal stem cells under inflammation

Osteoporosis is a common disease that affects patient quality of life, especially among the elderly population. Although inflammation contributes significantly to osteoporosis, the underlying mechanism is unclear. In this study, we found that tumor necrosis factor (TNF)-α, an inflammatory environmen...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Bone Res
Main Authors: Kuang, Wei, Zheng, Liwei, Xu, Xin, Lin, Yao, Lin, Jiong, Wu, Jiahua, Tan, Jiali
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698258/
https://ncbi.nlm.nih.gov/pubmed/29167750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/boneres.2017.37
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