WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis

Puberty is characterized by dynamic tissue remodeling in the mammary gland involving ductal elongation, resolution into the mature epithelial bilayer, and lumen formation. To decipher the cellular mechanisms underlying these processes, we studied the fate of putative stem cells, termed cap cells, pr...

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發表在:Dev Cell
Main Authors: Sreekumar, Amulya, Toneff, Michael J., Toh, Eajer, Roarty, Kevin, Creighton, Chad J., Belka, George K., Lee, Dong-Kee, Xu, Jianming, Chodosh, Lewis A., Richards, JoAnne S., Rosen, Jeffrey M.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698144/
https://ncbi.nlm.nih.gov/pubmed/29103953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.10.007
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