Glutamylation regulates transport, specializes function, and sculpts the structure of cilia

Ciliary microtubules (MTs) are extensively decorated with post-translational modifications (PTMs), such as glutamylation of tubulin tails. PTMs and tubulin isotype diversity act as a “Tubulin Code” that regulates cytoskeletal stability and the activity of MT-associated proteins such as kinesins. We...

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Publicat a:Curr Biol
Autors principals: O’Hagan, Robert, Silva, Malan, Nguyen, Ken C. Q., Zhang, Winnie, Bellotti, Sebastian, Ramadan, Yasmin H., Hall, David H., Barr, Maureen M.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5698134/
https://ncbi.nlm.nih.gov/pubmed/29129530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2017.09.066
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