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Nonlinear dynamics of early atherosclerotic plaque formation may determine the efficacy of high density lipoproteins (HDL) in plaque regression

We use a computational model to explore the effect of foam cell accumulation on plaque regression following an increase in high density lipoprotein (HDL) influx into the plaque. Atherosclerotic plaque formation is the outcome of cellular and cytokine responses to low density lipoproteins (LDL) that...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chalmers, Alexander D., Bursill, Christina A., Myerscough, Mary R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697811/
https://ncbi.nlm.nih.gov/pubmed/29161303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187674
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