Naja Naja Oxiana Venom Fraction Selectively Induces ROS-Mediated Apoptosis in Human Colorectal Tumor Cells by Directly Targeting Mitochondria

OBJECTIVE: To investigate the selective effect of Naja naja oxiana crude venom and its fractions on human colorectal cancer mitochondria to activate apoptosis signaling. METHODS: Cells and mitochondria isolated from human cancerous and normal colorectal tissues exposed to N. oxiana crude venom and i...

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Publicat a:Asian Pac J Cancer Prev
Autors principals: Fakhri, Amir, Omranipour, Ramesh, Fakhri, Sara, Mirshamsi, Mohammadreza, Zangeneh, Fatemeh, Vatanpour, Hossein, Pourahmad, Jalal
Format: Artigo
Idioma:Inglês
Publicat: West Asia Organization for Cancer Prevention 2017
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5697481/
https://ncbi.nlm.nih.gov/pubmed/28843256
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22034/APJCP.2017.18.8.2201
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