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Intertwined Precursor Supply during Biosynthesis of the Catecholate–Hydroxamate Siderophores Qinichelins in Streptomyces sp. MBT76

[Image: see text] The explosive increase in genome sequencing and the advances in bioinformatic tools have revolutionized the rationale for natural product discovery from actinomycetes. In particular, this has revealed that actinomycete genomes contain numerous orphan gene clusters that have the pot...

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Bibliografiske detaljer
Udgivet i:ACS Chem Biol
Main Authors: Gubbens, Jacob, Wu, Changsheng, Zhu, Hua, Filippov, Dmitri V., Florea, Bogdan I., Rigali, Sébastien, Overkleeft, Herman S., van Wezel, Gilles P.
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2017
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696649/
https://ncbi.nlm.nih.gov/pubmed/28945067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00597
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