High Concentrations of Rosiglitazone Reduce mRNA and Protein Levels of LRP1 in HepG2 Cells

Low-density lipoprotein receptor-related protein 1 (LRP1) is an endocytic receptor involved in the uptake of a variety of molecules, such as apoE, α2-macroglobulin, and the amyloid β peptide (Aβ), for either transcellular transport, protein trafficking or lysosomal degradation. The LRP1 gene can be...

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發表在:Front Pharmacol
Main Authors: Rondón-Ortiz, Alejandro N., Lino Cardenas, Christian L., Martínez-Málaga, Jimena, Gonzales-Urday, Ana L., Gugnani, Kuljeet S., Böhlke, Mark, Maher, Timothy J., Pino-Figueroa, Alejandro J.
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2017
主題:
Pharmacology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696635/
https://ncbi.nlm.nih.gov/pubmed/29201005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00772
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