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Beyond detoxification: a role for mouse mEH in the hepatic metabolism of endogenous lipids
Microsomal and soluble epoxide hydrolase (mEH and sEH) fulfill apparently distinct roles: Whereas mEH detoxifies xenobiotics, sEH hydrolyzes fatty acid (FA) signaling molecules and is thus implicated in a variety of physiological functions. These epoxy FAs comprise epoxyeicosatrienoic acids (EETs) a...
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| Publicado no: | Arch Toxicol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5696502/ https://ncbi.nlm.nih.gov/pubmed/28975360 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00204-017-2060-4 |
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