Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling

The mammary epithelium comprises two primary cellular lineages, but the degree of heterogeneity within these compartments and their lineage relationships during development remain an open question. Here we report single-cell RNA profiling of mouse mammary epithelial cells spanning four developmental...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Pal, Bhupinder, Chen, Yunshun, Vaillant, François, Jamieson, Paul, Gordon, Lavinia, Rios, Anne C., Wilcox, Stephen, Fu, Naiyang, Liu, Kevin He, Jackling, Felicity C., Davis, Melissa J., Lindeman, Geoffrey J., Smyth, Gordon K., Visvader, Jane E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696379/
https://ncbi.nlm.nih.gov/pubmed/29158510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01560-x
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