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Annexin A4 and A6 induce membrane curvature and constriction during cell membrane repair

Efficient cell membrane repair mechanisms are essential for maintaining membrane integrity and thus for cell life. Here we show that the Ca(2+)- and phospholipid-binding proteins annexin A4 and A6 are involved in plasma membrane repair and needed for rapid closure of micron-size holes. We demonstrat...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Boye, Theresa Louise, Maeda, Kenji, Pezeshkian, Weria, Sønder, Stine Lauritzen, Haeger, Swantje Christin, Gerke, Volker, Simonsen, Adam Cohen, Nylandsted, Jesper
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696365/
https://ncbi.nlm.nih.gov/pubmed/29158488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01743-6
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