Tissue-engineered composite scaffold of poly(lactide-co-glycolide) and hydroxyapatite nanoparticles seeded with autologous mesenchymal stem cells for bone regeneration

Objective: A new therapeutic strategy using nanocomposite scaffolds of grafted hydroxyapatite (g-HA)/poly(lactide-co-glycolide) (PLGA) carried with autologous mesenchymal stem cells (MSCs) and bone morphogenetic protein-2 (BMP-2) was assessed for the therapy of critical bone defects. At the same tim...

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Bibliographic Details
Published in:J Zhejiang Univ Sci B
Main Authors: Zhang, Bing, Zhang, Pei-biao, Wang, Zong-liang, Lyu, Zhong-wen, Wu, Han
Format: Artigo
Language:Inglês
Published: Zhejiang University Press 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696315/
https://ncbi.nlm.nih.gov/pubmed/29119734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1631/jzus.B1600412
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