Design, synthesis, in silico and in vitro antimicrobial screenings of novel 1,2,4-triazoles carrying 1,2,3-triazole scaffold with lipophilic side chain tether

BACKGROUND: 1,2,4-Triazoles and 1,2,3-triazoles have gained significant importance in medicinal chemistry. RESULTS: This study describes a green, efficient and quick solvent free click synthesis of new 1,2,3-triazole-4,5-diesters carrying a lipophilic side chain via 1,3-dipolar cycloaddition of diet...

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Detalhes bibliográficos
Publicado no:Chem Cent J
Main Authors: Aouad, Mohamed Reda, Mayaba, Mariem Mohammed, Naqvi, Arshi, Bardaweel, Sanaa K., Al-blewi, Fawzia Faleh, Messali, Mouslim, Rezki, Nadjet
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696273/
https://ncbi.nlm.nih.gov/pubmed/29159721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13065-017-0347-4
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