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MicroRNA-21 inhibits mitochondria-mediated apoptosis in keloid

MicroRNA-21 acts as an oncogene by promoting cell proliferation and migration, whereas inhibiting apoptosis in majority of cancers. MicroRNA-21 is upregulated in human keloid fibroblasts. We hypothesized that microRNA-21 may contribute to pathogenesis of keloid fibroblasts. First, enhanced miR-21 bu...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Wu, Hao, Wang, Jie, Ma, Hui, Xiao, Zhibo, Dong, Xiaoqun
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696232/
https://ncbi.nlm.nih.gov/pubmed/29190966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21656
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