A cassaine diterpene alkaloid, 3β-acetyl-nor-erythrophlamide, suppresses VEGF-induced angiogenesis and tumor growth via inhibiting eNOS activation

Angiogenesis is one of the hallmarks of cancer, playing an essential role in tumor growth, invasion, and metastasis. 3β-Acetyl-nor-erythrophlamide (3-ANE), a cassaine diterpene alkaloid compound from Erythrophleum fordii, exerts various pharmacological effects, including antitumor activity. However,...

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Publicat a:Oncotarget
Autors principals: Tae, Nara, Hung, Tran Manh, Kim, Okwha, Kim, Namho, Lee, Suhyun, Na, Sunghun, Min, Byung-Sun, Lee, Jeong-Hyung
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2017
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696186/
https://ncbi.nlm.nih.gov/pubmed/29190920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21307
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