MicroRNA-212/ABCG2-axis contributes to development of imatinib-resistance in leukemic cells

BCR-ABL-independent resistance against tyrosine kinase inhibitor is an emerging problem in therapy of chronic myeloid leukemia. Such drug resistance can be linked to dysregulation of ATP-binding cassette (ABC)-transporters leading to increased tyrosine kinase inhibitor efflux, potentially caused by...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Kaehler, Meike, Ruemenapp, Johanna, Gonnermann, Daniel, Nagel, Inga, Bruhn, Oliver, Haenisch, Sierk, Ammerpohl, Ole, Wesch, Daniela, Cascorbi, Ingolf, Bruckmueller, Henrike
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5696160/
https://ncbi.nlm.nih.gov/pubmed/29190894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.21272
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