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A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase
The positive-strand RNA virus Turnip yellow mosaic virus (TYMV) encodes an ovarian tumor (OTU)-like protease/deubiquitinase (PRO/DUB) protein domain involved both in proteolytic processing of the viral polyprotein through its PRO activity, and in removal of ubiquitin chains from ubiquitylated substr...
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| 出版年: | PLoS Pathog |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Public Library of Science
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695851/ https://ncbi.nlm.nih.gov/pubmed/29117247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006714 |
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