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A mobile loop near the active site acts as a switch between the dual activities of a viral protease/deubiquitinase
The positive-strand RNA virus Turnip yellow mosaic virus (TYMV) encodes an ovarian tumor (OTU)-like protease/deubiquitinase (PRO/DUB) protein domain involved both in proteolytic processing of the viral polyprotein through its PRO activity, and in removal of ubiquitin chains from ubiquitylated substr...
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| Publicado no: | PLoS Pathog |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695851/ https://ncbi.nlm.nih.gov/pubmed/29117247 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006714 |
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