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Penetrance and the Healthy Elderly

The variable penetrance of pathogenic variants (PVs) represents a major challenge to the field of human genetics, often complicating clinical decision-making and risk management. Nonpenetrance, the detection of PVs in the absence of disease manifestation, is a common phenomenon, yet, we know very li...

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Detalhes bibliográficos
Publicado no:Genet Test Mol Biomarkers
Main Authors: Lacaze, Paul, Winship, Ingrid, McNeil, John
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695739/
https://ncbi.nlm.nih.gov/pubmed/28876137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/gtmb.2017.0126
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