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Meta-analysis of time-to-event outcomes from randomized trials using restricted mean survival time: application to individual participant data

Meta-analysis of time-to-event outcomes using the hazard ratio as a treatment effect measure has an underlying assumption that hazards are proportional. The between-arm difference in the restricted mean survival time is a measure that avoids this assumption and allows the treatment effect to vary wi...

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Detalhes bibliográficos
Publicado no:Stat Med
Main Authors: Wei, Yinghui, Royston, Patrick, Tierney, Jayne F., Parmar, Mahesh K. B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695659/
https://ncbi.nlm.nih.gov/pubmed/26099573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/sim.6556
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