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Insulin resistance enhances the mitogen-activated protein kinase signaling pathway in ovarian granulosa cells

The ovary is the main regulator of female fertility. Granulosa cell dysfunction may be involved in various reproductive endocrine disorders. Here we investigated the effect of insulin resistance on the metabolism and function of ovarian granulosa cells, and dissected the functional status of the mit...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Kong, Linghui, Wang, Qien, Jin, Jiewen, Xiang, Zou, Chen, Taoyu, Shen, Shanmei, Wang, Hongwei, Gao, Qian, Wang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5695281/
https://ncbi.nlm.nih.gov/pubmed/29125859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0188029
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