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Differences of statin activity in 2D and 3D pancreatic cancer cell cultures
PURPOSE: To evaluate the anticancer activity of lovastatin (LOVA), mevastatin (MEVA), pitavastatin (PITA), and simvastatin (SIMVA) in 2D and 3D models of three human pancreatic cancer cell lines (BxPC-3, MIA PaCa-2, and PANC-1). METHODS: The effect of statins on cell viability was estimated by 3-(4,...
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| Pubblicato in: | Drug Des Devel Ther |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Dove Medical Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5695256/ https://ncbi.nlm.nih.gov/pubmed/29180851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S149411 |
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